Nucleosides (Ribose / 2′-Deoxy) Adenosine Guanosine Cytidine Uridine Thymidine 2′-OMe A/G/C/U 2′-F U / 2′-F C 2′-OMOE A/G/C/U cEt T LNA Nucleosides Pseudouridine (Ψ) m1Ψ (N1-Me-Ψ) 5-Methyl-C (5mC) 5-hmC rNTPs: ATP / GTP / CTP / UTP dNTPs: dATP / dGTP / dCTP / dTTP Modified NTPs Mono/Di/Triphosphates Cap Analogues (m7G, ARCA) Nucleosides (Ribose / 2′-Deoxy) Adenosine Guanosine Cytidine Uridine Thymidine 2′-OMe A/G/C/U 2′-F U / 2′-F C 2′-OMOE A/G/C/U cEt T LNA Nucleosides Pseudouridine (Ψ) m1Ψ (N1-Me-Ψ) 5-Methyl-C (5mC) 5-hmC rNTPs: ATP / GTP / CTP / UTP dNTPs: dATP / dGTP / dCTP / dTTP Modified NTPs Mono/Di/Triphosphates Cap Analogues (m7G, ARCA)

Nucleosides and Nucleotides

CCS offers an extensive range of nucleosides, phosphoramidites, linkers, and reagents from laboratory to bulk manufacturing scale. Our product portfolio includes high-purity DNA, RNA, LNA, and GalNAc-conjugated derivatives and intermediates, along with a variety of spacers, linkers, and synthetic building blocks. With proven expertise in carbohydrate and phosphorus chemistry, CCS provides tailored, end-to-end solutions for oligonucleotide synthesis, drug development, and advanced biochemical research.

  • Expertise in pentose and hexose sugar derivatives – mono-, di-, and oligosaccharides
  • Advanced protection and de-protection strategies in carbohydrate chemistry
  • Comprehensive glycosylation expertise – O-, N-, and C-glycosylation
  • In-house phosphorus chemistry capabilities, including large-scale amidite manufacturing
  • Specialized GalNAc-based linker technology, inversion chemistry, and halo substitution

Bench → Bulk

Nucleosides & Nucleotides

Nucleosides and nucleotides with 2′-OMe / 2′-F / 2′-OMOE / cEt / LNA options, plus r/dNTPs and cap analogues—delivering to various industries.

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Sugars & Backbones
Ribose · 2′-Deoxy · 2′-OMe/2′-F/2′-OMOE/cEt/LNA
Phosphates
rNTP · dNTP · Mono/Di/Triphosphates · Caps
Scale & QC
Lab → Kg · HPLC/LC-MS

Nucleosides

  • A/G/C/U/T cores
  • 2′-OMe, 2′-F, 2′-OMOE, cEt, LNA options
  • Pseudouridine (Ψ), m¹Ψ, 5mC, 5-hmC

Nucleotides & Caps

  • rNTPs & dNTPs; modified NTPs
  • Mono/Di/Triphosphates
  • Cap analogues (m7G, ARCA)

Scale & QC

  • Reactor scale-up; freeze-dry compatible
  • HPLC/LC-MS release testing
  • Process documentation
Adenosine Guanosine Cytidine Uridine Thymidine 2′-OMe A/G/C/U 2′-F U / 2′-F C 2′-OMOE A/G/C/U cEt T LNA Nucleosides Pseudouridine (Ψ) m¹Ψ (N1-Me-Ψ) 5-Methyl-C (5mC) 5-hmC rNTPs: ATP/GTP/CTP/UTP dNTPs: dATP/dGTP/dCTP/dTTP Modified NTPs Mono/Di/Triphosphates Cap Analogues (m7G/ARCA) Adenosine Guanosine Cytidine Uridine Thymidine 2′-OMe A/G/C/U 2′-F U / 2′-F C 2′-OMOE A/G/C/U cEt T LNA Nucleosides Pseudouridine (Ψ) m¹Ψ (N1-Me-Ψ) 5-Methyl-C (5mC) 5-hmC rNTPs: ATP/GTP/CTP/UTP dNTPs: dATP/dGTP/dCTP/dTTP Modified NTPs Mono/Di/Triphosphates Cap Analogues (m7G/ARCA)

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